News

Human papillomaviruses (HPVs) cause more than five percent all human cancers worldwide, yet for many, current treatments are ineffective. Dohun Pyeon, an MSU professor in the Department of Microbiology and Molecular Genetics in the College of Natural Science, has received a 2023 Strategic Partnership Grant; the MSU Research Foundation is funding his work on the development of a new immunotherapy for HPV-associated cancers. As one of just three recipients for 2023, Pyeon will receive $480,000 over three years to help his lab reach its long-term goal of developing an inexpensive immunotherapy.

Internationally renowned cancer researcher Olorunseun “Seun” Ogunwobi will join Michigan State University on Aug. 16 as chair of the Department of Biochemistry and Molecular Biology (BMB), which is affiliated with the College of Natural Science, the College of Human Medicine and the College of Osteopathic Medicine. He will also serve as co-director of the forthcoming Center for Cancer Health Equity Research at MSU.

Michigan State University Geoffrey Laumet and members of his lab are part of an international team that found an existing drug that may help decrease the side effects of cisplatin, a widely used cancer treatment that was discovered at MSU in 1965. The team, consisting of scientists from MSU, the University of Lille, the University of Strausburg, the Pasteur Institute of Lille in France, and the University of Coimbra in Portugal, has found that istradefylline, a drug already approved by the FDA and used to treat Parkinson’s disease, can reduce the side effects of cisplatin, while preserving its cancer-fighting strength.

When thinking about why breast cancer develops, it is critical to understand how normal development works. Recently, the National Institutes of Health awarded MSU physiology professor Eran Andrechek a five-year, $2.5 million grant to fund his research project of defining the role of the repressor E2F5 gene in mammary gland development.  in addition to a providing better understanding of the developmental biology, Andrechek hopes the findings will lead to further research on breast cancer.

MSU researchers are unveiling and studying chemical clues that could lead to better diagnoses and treatments for a metastatic form of breast cancer. Sophia Lunt, associate professor in the MSU Department of Biochemistry and Molecular Biology and her team—whose research focuses on understanding the role of metabolism in metastasis—are now reporting results from their work on triple negative breast cancer and how it spreads to other parts of the body. Lunt’s latest research, funded in part by a new $2 million grant from the National Institutes of Health, was recently published in the journal Nature on May 18.